Thyroid auto-antibody test

Thyroid auto-antibody test

Species: Canine

Specimen: 1 mL serum

Container: Plain (red top) tube

Collection protocol: Standard venepuncture

Special handling/shipping requirements:

Samples should be transported to the lab within 12-24 hours

General information about the disease:

Hypothyroidism is the most common disease condition of the canine thyroid glands. Canine lymphocytic thyroiditis is believed to cause of about 50% of cases of canine hypothyroidism. Hypothyroidism does not occur until a large amount of the thyroid gland is non-functional, and sub clinical lymphocytic thyroiditis is present for some time before clinical signs of hypothyroidism emerge and total serum T4 and T3 concentrations decrease.

The best test to diagnose this condition is considered to be the thyroglobulin autoantibody test. All dogs with thyroglobulin autoantibodies are considered to have lymphocytic thyroiditis and this test is both sensitive and specific for the condition. A dog may have antibodies present but may not yet be hypothyroid. It is recommended that dogs with thyroglobulin autoantibodies be monitored regularly for signs of hypothyroidism. Of 171 dogs monitored with thyroglobulin auto-antibodies, 20% became hypothyroid in the following year.

General information about when this test is indicated:

See “Diagnosis and monitoring of hypothyroidism”.

Comparison with other related tests:

See “Diagnosis and monitoring of hypothyroidism”.